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New research identifies potential treatment target in fatty liver disease

Metabolic dysfunction-associated steatotic liver disease (MASLD) can cause more serious liver conditions, such as liver failure. A new study, led by Lund University in Sweden, presents new data that may lead to better disease management and prevention of in the future. The international research team identified an altered expression of specific genes in samples from individuals with obesity, MASLD

https://www.ludc.lu.se/article/new-research-identifies-potential-treatment-target-fatty-liver-disease - 2026-04-29

A genetic brake that forms our muscles

In an international study, researchers at Lund University in Sweden have identified a gene variant that controls the body’s capability to form new blood vessels in muscles – a mechanism that affects physical performance, health and recovery. The favourable gene variant is considerably more common among top athletes in endurance sports, compared with both top athletes in explosive sports and non-at

https://www.ludc.lu.se/article/genetic-brake-forms-our-muscles - 2026-04-29

Mapping of gene variants which affect gut microbiota and disease risk

Studies of the gut microbiota can provide new knowledge about human health and how the risk of developing various diseases is affected. Marju Orho-Melander at Lund University is one of the authors of two new articles in Nature Genetics which have discovered several new gene variants in the human genome which may influence which bacteria are found in the gut. Some of the new gene variants can be li

https://www.ludc.lu.se/article/mapping-gene-variants-which-affect-gut-microbiota-and-disease-risk - 2026-04-29

Lund initiates genetic sequencing study in diabetes families to provide new insights into what causes the disease

This article is over 5 years old, and the information may therefore be outdated. Lund University Diabetes Centre has entered into a collaboration with the Regeneron Genetics Center LLC (RGC) and the University of Helsinki involving exome-sequencing and whole genome array genotyping of greater than 9,000 individuals. The collaboration will involve the largest sequencing study in diabetes families t

https://www.ludc.lu.se/article/lund-initiates-genetic-sequencing-study-diabetes-families-provide-new-insights-what-causes-disease - 2026-04-29

Antibiotics can have long-term effect on gut microbiota

Antibiotic treatments help the body to fight infections and should have as little negative impact on humans as possible. A new study in the journal Nature Medicine shows that the use of antibiotics can affect the human gut microbiota for several years. The study found that some types of antibiotics had a greater impact on the gut microbiota than others. “It is great that we have antibiotics which

https://www.ludc.lu.se/article/antibiotics-can-have-long-term-effect-gut-microbiota - 2026-04-29

THADA - new findings in the role of the mother in type 2 diabetes

This article is over 5 years old, and the information may therefore be outdated. Research from Lund University in Sweden can explain why type 2 diabetes is inherited to a greater extent from an individual’s mother. The heredity of a previously known risk gene, THADA, has proven to be dominant if it comes from the mother, whereas it has little or no effect on the child’s risk of disease if it origi

https://www.ludc.lu.se/article/thada-new-findings-role-mother-type-2-diabetes - 2026-04-29

Climate-friendly diet yielded unexpectedly strong nutritional outcomes

That eating plenty of vegetables, wholegrains and legumes is beneficial for health is well known. More surprising, however, is that people who eat in a environmentally-friendly way also display nutritional values that are better than researchers had expected. This is shown in a new study from Lund University. The EAT–Lancet diet is a global dietary guideline developed to promote both human health

https://www.ludc.lu.se/article/climate-friendly-diet-yielded-unexpectedly-strong-nutritional-outcomes - 2026-04-29

Researchers predict coronary heart disease in diabetes subgroup

A growing body of research shows that diabetes can be stratified into five different subgroups. Researchers at Lund University have now investigated whether a person’s genetic predisposition to different diabetes subgroups can help assess the risk of developing coronary artery disease. The team created genetic risk scores and found that the scores for one subgroup could predict coronary artery dis

https://www.ludc.lu.se/article/researchers-predict-coronary-heart-disease-diabetes-subgroup - 2026-04-29

New research shows how blood sugar-regulating cells change in type 2 diabetes

Researchers at Lund University in Sweden have carried out the most detailed mapping to date of the epigenome in the cells that regulate the body’s blood sugar levels. The study, published in Nature Metabolism, shows how chemical changes to DNA affect both insulin-producing beta cells and glucagon-producing alpha cells – and how these patterns change in type 2 diabetes. All cells in the body have t

https://www.ludc.lu.se/article/new-research-shows-how-blood-sugar-regulating-cells-change-type-2-diabetes - 2026-04-29

New findings explain the connection between melatonin and type 2 diabetes

This article is over 5 years old, and the information may therefore be outdated. A new experimental and clinical study from Lund University in Sweden shows that the sleep hormone melatonin impairs insulin secretion in people with a common gene variant.

“This could explain why the risk of type 2 diabetes is greater among, for instance, overnight workers or people with sleeping disorders”, says Pro

https://www.ludc.lu.se/article/new-findings-explain-connection-between-melatonin-and-type-2-diabetes - 2026-04-29

New findings can lead to a new principle for treating diabetic kidney damage

This article is over 5 years old, and the information may therefore be outdated. One in three people with diabetes will face some form of renal impairment in the course of their lives. Studies conducted by researchers at the Lund University Diabetes Centre may lead to the development of an entirely new principle for treating type 2 diabetes and preventing kidney damage in the future. Previous anal

https://www.ludc.lu.se/article/new-findings-can-lead-new-principle-treating-diabetic-kidney-damage - 2026-04-29

New findings can lead to a new principle for treating diabetic kidney damage

This article is over 5 years old, and the information may therefore be outdated. One in three people with diabetes will face some form of renal impairment in the course of their lives. Studies conducted by researchers at the Lund University Diabetes Centre may lead to the development of an entirely new principle for treating type 2 diabetes and preventing kidney damage in the future. Previous anal

https://www.ludc.lu.se/article/new-findings-can-lead-new-principle-treating-diabetic-kidney-damage-0 - 2026-04-29

Focus on personalized treatment of type 2 diabetes and cardiovascular disease

This article is over 5 years old, and the information may therefore be outdated. The European Research Council makes a large investment in diabetes research. A project led by Professor Paul Franks at Lund University Diabetes Centre is to develop methods that can be used in the design of preventive treatment for type 2 diabetes and cardiovascular disease. - Through this project we will use function

https://www.ludc.lu.se/article/focus-personalized-treatment-type-2-diabetes-and-cardiovascular-disease - 2026-04-29

Obesity reprogrammes muscle stem cells

This article is over 5 years old, and the information may therefore be outdated. Obesity is associated with reduced muscle mass and impaired metabolism. Epigenetic changes that affect the formation of new muscle cells may be a contributing factor, according to new research from Lund University, Sweden. In a new study, doctoral student Cajsa Davegårdh has studied so-called DNA methylation in muscle

https://www.ludc.lu.se/article/obesity-reprogrammes-muscle-stem-cells - 2026-04-29

An Innovative Medicines Initiative Project for Precision Medicine in DKD

This article is over 5 years old, and the information may therefore be outdated. BEAt-DKD (“Biomarker Enterprise to Attack Diabetic Kidney Disease”), a unique public private partnership funded by the Innovative Medicines Initiative (IMI), member companies from the European Federation of Pharmaceutical Industries and Associations (EFPIA), the Juvenile Diabetes Research Foundation (JDRF) and the sta

https://www.ludc.lu.se/article/innovative-medicines-initiative-project-precision-medicine-dkd - 2026-04-29

100 million SEK for personalized medicine in Diabetes

This article is over 5 years old, and the information may therefore be outdated. Almost 0.5 billion people have diabetes globally, many of whom are unaware of their condition; within the next two decades, this number is expected to double, largely owing to a growing, ageing, and increasingly industrialized global population. Lund University receives 100 million SEK from The Swedish Foundation of S

https://www.ludc.lu.se/article/100-million-sek-personalized-medicine-diabetes - 2026-04-29

Unique mapping of methylome in insulin-producing islets

This article is over 5 years old, and the information may therefore be outdated. Throughout our lives, our genes are affected by the way we live. Diet, exercise, age and diseases create imprints that are stored in something called methylome. Now, for the first time, researchers at the Lund University Diabetes Centre in Sweden have been able to map the entire methylome in the pancreatic islets whic

https://www.ludc.lu.se/article/unique-mapping-methylome-insulin-producing-islets - 2026-04-29

Successful research funded by the European Research Council

This article is over 5 years old, and the information may therefore be outdated. Six researchers from Lund University Diabetes Centre have recieved prestigous grants from the European Research Council (ERC). In order to celebrate the success we invited the public to an open seminar. Some of the talks can be reviewed here (in Swedish). Forskning för bättre folkhälsa:Framsteg inom typ 2-diabetes, fe

https://www.ludc.lu.se/article/successful-research-funded-european-research-council - 2026-04-29

From injections to pills - the research on neonatal diabetes

This article is over 5 years old, and the information may therefore be outdated. They govern everything we think and do, they give us the ability to feel pain and to secrete insulin: they are the ion channels that are present in every one of our cells and that control the electrical impulses in our nerve and muscle cells. “For me, they are the very spark of life”, says Dame Frances Ashcroft, profe

https://www.ludc.lu.se/article/injections-pills-research-neonatal-diabetes - 2026-04-29

200.000 euro to diabetes research

This article is over 5 years old, and the information may therefore be outdated. Four researchers have been awarded grants from The Bo and Kerstin Hjelt Diabetes Foundation. The grant consists of Euro 50 000 each and are aiming towards better treatments and prevention of type 2-diabetes. Improved life expectancy and quality of people with diabetesDiabetes affects millions of patients around the wo

https://www.ludc.lu.se/article/200000-euro-diabetes-research - 2026-04-29